WARNING:
If you are running Windows 11, be careful with the recent Cumulative Update (KB5007262).

My MSFS crashed to desktop after 5 to 10 minutes running.

I can confirm that on my system since I experienced the same situation twice in the last few days.

The first time was last Friday, in which I mistook the CTD was caused by the motherboard drivers I updated at the same time.

Today I had the Windows Cumulative Update installed alone, which consequently led to the same MSFS CTD scenerio after less than 10 minutes running.

Luckily, both CTDs were fixed by restoring the OS drive (just Windows, excluding MSFS) from the last backup before the update.

I haven’t Googled the issue if any other had ran into the same situation yet.  Probably there are explanations and fixes to the CTD.  But in my case, restoring the whole Windows drive is the most time-efficient solution to me.

If you are running Windows 11 and had the update installed already without any issue, Congratulations !

If you are running Windows 11 and haven’t had the KB5007262 update installed yet, do be careful either by making a system back up first (just in case) or simply skipping it for good.

Have reported the issue to Zendesk, and got a reply saying “the issue has been tracked in our internal bug tracker.”

Hope there will be a solution coming soon.